Nothando Mangena

Enteroendocrine cells play a major role in sensing the luminal contents of the gut and communicating with other organs such as the pancreas, liver and brain. The gut-brain connection is essential in the regulation of food intake…

INTRODUCTION: Enteroendocrine cells (EEC) secrete satiety hormones Glucagon-like peptide 1 (GLP-1) and Peptide YY (PYY) in response to luminal content through nutrient-sensing GPCRs…