Nicholas Talley

BACKGROUND: Our team (Xiong et al. 2021) recently developed an infliximab population pharmacokinetic (popPK) model in children and young adults with Crohn’s disease (CD). We found that prediction accuracy improved when all five covariates of drug clearance were included…

BACKGROUND: Despite rapidly increasing global burden of metabolic-associated fatty liver disease (MAFLD), therapeutic options remain limited. Dietary modulation is a key component of MAFLD management, with reduced energy intake for weight loss considered first line therapy…

Disorders of Gut-Brain Interaction (DGBI) are chronic, remitting and relapsing conditions which may originate in childhood. Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are two most common DGBIs seen in clinical practice…