N. Jewel Samadder

Early-onset colorectal cancer (CRC diagnosed before age 50) has risen worldwide, with an increasing number of survivors of reproductive age. We aimed to investigate the risk of adverse pregnancy and neonatal outcomes among early-onset CRC survivors…

_BACKGROUND AND AIMS: _Preclinical data shows mTOR pathway upregulation in Familial Adenomatous Polyposis (FAP). Inhibition of this pathway by rapalogues, like rapamycin, suggests promising results, but poor drug bioavailability and toxicity limited effective use of these drugs in FAP trials…