Michael Kappelman

BACKGROUND: Tumor necrosis factor inhibitors (TNFi) are a mainstay of pediatric Crohn’s disease (PCD) therapy; yet not all patients respond, and others lose response over time. Combination therapy with methotrexate may improve response; however, this has not been rigorously evaluated…

BACKGROUND: Perianal fistulizing complications (PFC) of Crohn’s disease (CD) are highly morbid and difficult to treat. Despite the advent of biologic medications, antibiotics remain a mainstay of PFC treatment…

BACKGROUND & AIMS: Hispanics account for 19% (62 million) of the US population, of whom 2/3rd are US born; with global and regional immigration patterns, Hispanics are expected to increase to 30% of the US population (111 million) by 2060…