Michael Kamm

BACKGROUND: After successful induction, a subset of patients with Crohn’s disease (CD) experience a secondary loss of response (LoR) to ustekinumab (UST) maintenance therapy. Dose intensification may assist in regaining response…

BACKGROUND The gut microbiome is central to Crohn’s disease (CD) pathogenesis but the relative contribution of different environmental factors to disease compositional variation is unknown…

The microbiome plays a central role in intestinal inflammation in IBD. It is influenced by environmental factors included diet…

BACKGROUND Emerging data support the importance of gut microbiome alterations in the pathogenesis of inflammatory bowel disease (IBD) but their role as non-invasive biomarkers for IBD has not been unexplored…

BACKGROUND The gut microbiome play an important role in Crohn’s disease (CD) pathogenesis. However, the extent to which interpersonal relations shape individual genetic makeup of the microbiome and its transmission in CD patients and their household members remains unknown…