Madhusudan Grover

Disorders of gut-brain interaction (DGBI), including irritable bowel syndrome (IBS) and functional dyspepsia (FD), are among the most common gastrointestinal (GI) disorders seen in primary care and GI practices. The pathophysiology is multifactorial and not well understood…

Disorders of gut-brain interaction (DGBI), including irritable bowel syndrome (IBS) and functional dyspepsia (FD), are among the most common gastrointestinal (GI) disorders seen in primary care and GI practices. The pathophysiology is multifactorial and not well understood…

DDW attendees will have the opportunity to learn about recent developments in biomarker-discovery for FGID/DGBI and Neurogastroenterology…

This session will focus on intercellular signaling mechanisms between neurons and non-neuronal cells that control gut motor functions…

SOCIETY: AGA

BACKGROUND: Idiopathic gastroparesis (IG) is an increasingly prevalent subtype of gastroparesis and causes significant morbidity and decreased quality of life…

SOCIETY: AGA

BACKGROUND: In irritable bowel syndrome (IBS), insufficient suppression of proteolytic activity (PA) leads to intestinal barrier disruption and visceral hypersensitivity. Our work shows host PA is suppressed by microbial β-glucuronidase (GUS) activity…

BACKGROUND: Approximately 15% of individuals develop post-infection irritable bowel syndrome (PI-IBS) after _Campylobacter_ infection. Our previous work shows 40% of PI-IBS patients have high fecal proteolytic activity (PA) and changes in microbiota composition…

INTRODUCTION: Alpha-Gal Syndrome (AGS) is an IgE-mediated allergic reaction to galactose-α-1,3-galactose (alpha-gal) induced by Lone Star tick bite with symptoms typically triggered by mammalian meat consumption…

SOCIETY: AGA

BACKGROUND: Interstitial cells of Cajal (ICC), electrically active cells found throughout the gastrointestinal tract, generate spontaneous electrical slow waves, and transmit these waves to smooth muscle cells in the gut to produce phasic contractions…