Longyuan Zhou

Intestinal fibrosis is a significant clinical challenge in inflammatory bowel diseases, but no effective anti-fibrotic therapy is currently available. GCGR and GLP1R are both peptide hormone receptors involved in energy metabolism of epithelial cells…

Backgrounds: Creeping fat, a hallmark of Crohn's disease (CD), is intimately associated with intestinal fibrosis, and the formation of strictures. Histology shows that extracellular matrix (ECM) remodeling exists in the area of creeping fat…