Long Nguyen

BACKGROUND: Aspirin has been known for its chemopreventive effect against various cancers. Evidence for the chemopreventive effect of the very long-term use of aspirin is still uncertain…

BACKGROUND The gut microbiome is central to Crohn’s disease (CD) pathogenesis but the relative contribution of different environmental factors to disease compositional variation is unknown…

BACKGROUND: Non-alcoholic steatohepatitis (NASH), a leading cause of liver-related morbidity and mortality, is highly prevalent in people living with HIV (PLWH).1 Microbial translocation (MT) associated with hepatic inflammation and fibrosis may play a critical role in NASH pathogenesis…

The microbiome plays a central role in intestinal inflammation in IBD. It is influenced by environmental factors included diet…

The microbiome plays a central role in intestinal inflammation in IBD. It is influenced by environmental factors included diet…

BACKGROUND AND AIMS: Chemoresistance is a major cause of colorectal cancer (CRC) recurrence and death. The critical role of gut microbiome in the efficacy of CRC chemotherapy remains unclear…

BACKGROUND: Diet is known to alter the risk of depression. Increasing data also demonstrate a causal role of the gut microbiome in mental illness, via the gut-brain axis. However, it remains unclear how diet and the microbiome mechanistically influence depression risk in humans…

We and others have demonstrated a tight coupling between dietary intake, gut microbial ecology, and near-term alterations in cardiometabolic biomarkers in the ZOE PREDICT-1 study (Zeevi 2015; Asnicar & Berry 2021)…

BACKGROUND: Through shotgun metagenomic sequencing, we identified the depletion of probiotic species_ Lactobacillus acidophilus_ in stools of mice with non-alcoholic fatty liver disease-associated hepatocellular carcinoma (NAFLD-HCC)…

Colorectal cancer (CRC) remains a leading cause of cancer related mortality worldwide…

BACKGROUND: Proton pump inhibitor (PPI) use has been linked to alterations in gut microbial communities, but prior studies have been limited to describing broad differences in microbial abundance…

BACKGROUND: Primary bile acids (PBA) and their gut microbial metabolites (secondary BA [SBA]) modulate immune function and can contribute to intestinal inflammation and tumorigenesis. Diet alters the production and metabolism of BAs…

INTRODUCTION: Although colonoscopy is considered an optimal method for detecting colorectal adenomas, it has limitations, such as frequent use of sedation and missed polyps…

Metabolic dysfunction-associated steatotic liver disease (MASLD) is highly prevalent and a leading cause of liver-related morbidity and mortality…

SOCIETY: AGA

BACKGROUND: Coupled with well-characterized host genetic susceptibilities and environmental risk factors, alterations of gut microbial communities contribute to risk and severity of the inflammatory bowel diseases (IBD) and their subtypes, Crohn’s disease (CD) and ulcerative colitis (UC)…

SOCIETY: AGA The session will provide insights into the complex interplay between nutrition, microbial communities and metabolic health…

INTRODUCTION: Controversies about the long-term health consequences of low-carbohydrate diets (LCD) persist…

This session will highlight how intestinal fungi mediate inflammation and how helminths contribute to mucosal immunity…