Lizi Hegarty

Appearances

ACONITATE DECARBOXYLASE 1 (ACOD1) REPRESENTS A CRUCIAL REGULATOR OF MONOCYTE RECRUITMENT, SURVIVAL AND PROINFLAMMATORY STATUS IN INTESTINAL INFLAMMATION
Date
May 8, 2023
Aconitate decarboxylase 1 (ACOD1; also known as IRG-1) is the ubiquitous source of the metabolite itaconate, which dampens inflammasome activation by preventing HIF1α production of IL-1β and prevents TNF production through NRF2 activation…
Presenter
Gareth-Rhys Jones
Speakers
Lizi Hegarty
Wouter T'Jonck
Claire Adams
Broc Drury
Adam Byrne
Gwo-Tzer Ho
Calum Bain