Lixian Chen

Appearances

KNOCKOUT (KO) OF NEUROKININ RECEPTOR 1 (NK1R) AMELIORATES LIVER PHENOTYPES IN AN ACUTE MODEL OF ALCOHOL-INDUCED LIVER DISEASE (ALD)
Date
May 9, 2023
BACKGROUND: Alcoholic hepatitis (AH) is a life-threatening form of alcohol-associated liver disease (ALD), with no effective therapy…
Presenter
Nipuni Punsara Barapula
Speakers
Tianhao Zhou
Lixian Chen
Nan Wu
Keisaku Sato
Konstantina Kyritsi
Lindsey Kennedy
Burcin Ekser
Corinn Marakovits
Heather Francis
Indiana University
Ludovica Ceci
Guido Carpino
Eugenio Gaudio
Romina Mancinelli
Gianfranco Alpini
Shannon Glaser
THE NOVEL AND SPECIFIC CHYMASE INHIBITOR, INVA8001, AMELIORATES THE PHENOTYPES OF PRIMARY SCLEROSING CHOLANGITIS (PSC) IN MDR2<sup>-/-</sup> MICE (MODEL OF PSC) BY DOWNREGULATION OF BILIARY SENESCENCE
Date
May 6, 2023
BACKGROUND: Chronic cholestatic liver diseases, such as primary sclerosing cholangitis (PSC), often lead to end-stage liver disease requiring liver transplantation. PSC also significantly increases the risk of cholangiocarcinoma (CCA)…
Presenter
Jessie Bernard
Speakers
Sameer Sharma
Meenakshi Chawla
Ashok Varma
Lindsey Kennedy
Tianhao Zhou
Debjyoti Kundu
Corinn Marakovits
Lixian Chen
Alison Meyer
Leah Smith
Burcin Ekser
Anita Ganjoo
Aman Kant
Steve Okada
Salvatore Alesci
Krishnan Nandabalan
Gianfranco Alpini
Heather Francis
Indiana University
MELATONIN THERAPY REDUCES BILIARY SENESCENCE, LIVER INFLAMMATION AND FIBROSIS IN A MURINE MODEL OF PRIMARY BILIARY CHOLANGITIS (PBC).
Date
May 8, 2023
AIMS: The mechanism of gut microbiota involved in the etiopathogenesis of primary cholangitis (PBC) remains unclear. Here, we investigated the role of gut microbiota in liver immune response in PBC…
Presenter
Lixian Chen
Speakers
Lindsey Kennedy
Ludovica Ceci
Nan Wu
Tianhao Zhou
Konstantina Kyritsi
Guido Carpino
Romina Mancinelli
Eugenio Gaudio
Alison Meyer
Howard Young
Nipuni Punsara Barapula
Burcin Ekser
Keisaku Sato
Jessie Bernard
Heather Francis
Indiana University
Shannon Glaser
Gianfranco Alpini
MAST CELLS (MCS) PROMOTE PRIMARY SCLEROSING CHOLANGITIS (PSC) PHENOTYPES IN MICE L-HISTIDINE DECARBOXYLASE KNOCKOUT (HDC<sup>-/-</sup>) MICE VIA MC-NFKB AND HEPATIC IL-33 SIGNALING
Date
May 8, 2023
AIMS: The mechanism of gut microbiota involved in the etiopathogenesis of primary cholangitis (PBC) remains unclear. Here, we investigated the role of gut microbiota in liver immune response in PBC…
Presenter
Corinn Marakovits
Speakers
Tianhao Zhou
Lixian Chen
Debjyoti Kundu
Jessie Bernard
Burcin Ekser
Leah Smith
Wenjun Zhang
Lindsey Kennedy
Gianfranco Alpini
Heather Francis
Indiana University
INHIBITION OF THE GNRH/GNRHR1 AXIS AMELIORATES THE PHENOTYPES OF PRIMARY BILIARY CHOLANGITIS (PBC).
Date
May 8, 2023
AIMS: The mechanism of gut microbiota involved in the etiopathogenesis of primary cholangitis (PBC) remains unclear. Here, we investigated the role of gut microbiota in liver immune response in PBC…
Presenter
Konstantina Kyritsi
Speakers
Tianhao Zhou
Lindsey Kennedy
Burcin Ekser
Nipuni Punsara Barapula
Keisaku Sato
Nan Wu
Lixian Chen
Corinn Marakovits
Heather Francis
Indiana University
Gianfranco Alpini