Leah Smith

Appearances

THE NOVEL AND SPECIFIC CHYMASE INHIBITOR, INVA8001, AMELIORATES THE PHENOTYPES OF PRIMARY SCLEROSING CHOLANGITIS (PSC) IN MDR2<sup>-/-</sup> MICE (MODEL OF PSC) BY DOWNREGULATION OF BILIARY SENESCENCE
Date
May 6, 2023
BACKGROUND: Chronic cholestatic liver diseases, such as primary sclerosing cholangitis (PSC), often lead to end-stage liver disease requiring liver transplantation. PSC also significantly increases the risk of cholangiocarcinoma (CCA)…
Presenter
Jessie Bernard
Speakers
Sameer Sharma
Meenakshi Chawla
Ashok Varma
Lindsey Kennedy
Tianhao Zhou
Debjyoti Kundu
Corinn Marakovits
Lixian Chen
Alison Meyer
Leah Smith
Burcin Ekser
Anita Ganjoo
Aman Kant
Steve Okada
Salvatore Alesci
Krishnan Nandabalan
Gianfranco Alpini
Heather Francis
Indiana University
MAST CELLS (MCS) PROMOTE PRIMARY SCLEROSING CHOLANGITIS (PSC) PHENOTYPES IN MICE L-HISTIDINE DECARBOXYLASE KNOCKOUT (HDC<sup>-/-</sup>) MICE VIA MC-NFKB AND HEPATIC IL-33 SIGNALING
Date
May 8, 2023
AIMS: The mechanism of gut microbiota involved in the etiopathogenesis of primary cholangitis (PBC) remains unclear. Here, we investigated the role of gut microbiota in liver immune response in PBC…
Presenter
Corinn Marakovits
Speakers
Tianhao Zhou
Lixian Chen
Debjyoti Kundu
Jessie Bernard
Burcin Ekser
Leah Smith
Wenjun Zhang
Lindsey Kennedy
Gianfranco Alpini
Heather Francis
Indiana University