Khushboo Gala

The Academy of Educators serves to support the careers of educators in GI/Hepatology. Our annual plenary session is an opportunity for those who identify as educators to build skills, strengthen our community, and celebrate the work being done by our junior colleagues…

BACKGROUND: Sound evidence support the effectiveness of the transoral outlet reduction (TORe) with full-thickness endoscopic suturing (FTS) or argon plasma coagulation (APC) alone to address post-RYGB weight regain…

BACKGROUND: The field of bariatric endoscopy continues to evolve with the introduction of new technology and refinement of endoscopic techniques. Recently, the gastric antrum has gained interest as a potential novel therapeutic target…

Background: Transoral outlet reduction endoscopy (TORe) has been shown to be effective in managing weight regain after Roux-en-Y gastric bypass (RYGB), as has the glucagon-like peptide-1 agonist, liraglutide. However, the effect of adjunctive liraglutide after TORe has yet to be assessed…

BACKGROUND: Our phenotype-guided approach to antiobesity medications is associated with greater weight loss compared to the obesity medicine standard of care…

Type II diabetes (T2D) pathogenesis is linked with diabetes-associated duodenal alterations, presenting a potential regnerative therapeutic target…

BACKGROUND: Obesity is considered a major risk factor for developing multiple complications and medical conditions including type-2 diabetes mellitus (T2DM). Multiple scores (i.e., Individualized Metabolic Surgery [IMS], DiaRem, advanced DiaRem, and Robert et Al…

INTRODUCTION: A phenotype-tailored lifestyle intervention (PLI) has shown superior outcomes when compared to a standard lifestyle intervention (SLI) in a 12-week trial (PMID: 37007741). However, phenotype testing for obesity is time-consuming, expensive, and not widely accessible…

BACKGROUND AND AIMS: The Primary Obesity Surgery Endoluminal 2.0 (POSE2.0) is an endoscopic gastric remodeling procedure that utilizes an incisionless operating platform (IOP, San Clemente, CA) to remodel the stomach and alter appetite (FIGURE 1)…

BACKGROUND: The duodenum is integral as a metabolic signaling center, making it a promising therapeutic target for Type 2 Diabetes (T2D). However, the specific pathophysiological alterations in the duodenum under metabolic stress, especially in human, are not well-understood…

BACKGROUND: Roux-en-Y Gastric Bypass (RYGB) is often preferred for patients with obesity and gastroesophageal reflux disease (GERD), as it typically reduces reflux symptoms. However, post-RYGB, GERD symptoms and the use of proton pump inhibitors (PPIs) remain prevalent…

Obesity and type-2 diabetes mellitus (T2DM) are two inter-related chronic diseases with significant medical and financial burden. T2DM results in detrimental vascular complications including microvascular and macrovascular diseases…