Keiko Maeda

BACKGROUND A defective gastrointestinal epithelial tight junction (TJ) barrier has been implicated as a key pathogenic factor in inflammatory bowel diseases (IBD) and other gut inflammatory conditions…

BACKGROUND AND AIMS: Intestinal fibrosis is a major contributor to the high operation rate in Crohn's disease (CD) while current precise biomarker at the early stage of fibrosis as well as the effective treatment targeting fibroblasts is lacking…