BACKGROUND: Aspirin has been known for its chemopreventive effect against various cancers. Evidence for the chemopreventive effect of the very long-term use of aspirin is still uncertain…
INTRODUCTION: The enzyme deoxyhypusine synthase (DHPS) conjugates the N-terminal moiety of the polyamine spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form a unique amino acid, hypusine…