Kai Yuan

BACKGROUND AND AIMS: The relationship between intratumoral fungi and the progression of colorectal cancer (CRC) is largely unclear. We aim to determine the structure of the fungal community within a neoplasia (adenoma or CRC) and its association with genetic mutation in adenoma and CRC…

BACKGROUND: _Clostridium butyricum_ is a known probiotic bacterium with anti-inflammatory activity. We found that it is depleted in patients with colorectal cancer (CRC) from multiple cohorts. Here, we examined the immunomodulatory effect of _C…