Joshua Noe

BACKGROUND: Given the variable response to anti-TNF therapy in patients with Crohn’s disease (CD), we hypothesized there is a core biologic (inflammatory) signature associated with early response and endoscopic healing (EH)…

BACKGROUND: Prior pharmacokinetic (PK) investigations have identified an association between anti-TNF trough concentrations (cTrough) and clinical or biochemical remission for children with Crohn’s Disease (CD)…