Jiayu Zhang

BACKGROUND: Perianal fistulae are highly morbid complications of Crohn’s disease (CD) with a cumulative incidence of 20-25%; despite demonstrated efficacy of infliximab treatment, estimates of complete resolution are only 20-30%. Ultimately, 20% of patients will require proctectomy…

BACKGROUND: PSC is a chronic inflammatory condition of the biliary epithelium characterized by concentric periductal fibrosis. As opposed to inflammatory bowel disease (IBD), a frequently overlapping trait, there are currently no drugs that definitively slow disease progression…