Jiande Chen

Enteroendocrine cells play a major role in sensing the luminal contents of the gut and communicating with other organs such as the pancreas, liver and brain. The gut-brain connection is essential in the regulation of food intake…

BACKGROUND: The gastrointestinal (GI) disturbance is a frequent complication in patients with thoracolumbar vertebral fracture (TVF), especially in the postoperative period. Laxatives are sometimes of limited effect…

BACKGROUND: Gastric dysmotility and gastric slow wave dysrhythmias have been well documented in patients with diabetes. However, little is known on the effect of hyperglycemia on small intestine motility such as intestinal slow waves, due to limited options in measuring its activity…

INTRODUCTION: Patients with upper gastrointestinal (UGI) symptoms of abdominal pain, nausea, vomiting, and bloating often complain within the postprandial period…

BACKGROUND & AIM: Despite advancements in pharmacotherapies, glycemia is poorly controlled in a large proportion of patients with type 2 diabetes (T2D). The vagus nerve regulates energy metabolism…

BACKGROUND AND OBJECTIVES: The deficiency of insulin synthesis in diabetes is attributed to a decrease of mRNA level transcribed in the pancreatic beta cell…

BACKGROUND & AIM: Gastrointestinal (GI) dysmotility is common in diabetes. However, little is known on the longitudinal alternations of GI motility during the development of type 2 diabetes mellitus (T2DM)…