BACKGROUND The gut microbiome is central to Crohn’s disease (CD) pathogenesis but the relative contribution of different environmental factors to disease compositional variation is unknown…
BACKGROUND: Through shotgun metagenomic sequencing, we identified the depletion of probiotic species_ Lactobacillus acidophilus_ in stools of mice with non-alcoholic fatty liver disease-associated hepatocellular carcinoma (NAFLD-HCC)…
BACKGROUND: Gut dysbiosis is associated with persistent multi-system symptoms following SARS-CoV-2 infection, or post-acute COVID-19 syndrome (PACS). We performed a randomised controlled trial to assess the effects of gut microbiome modulation on alleviation of PACS symptoms…
BACKGROUND: Post-acute COVID-19 syndrome (PACS) affects sleep and neuropsychiatric functions but treatment is limited. We aimed to assess the effects of faecal microbiota transplantation (FMT) in alleviating post-COVID insomnia and anxiety…
BACKGROUND Emerging data support the importance of gut microbiome alterations in the pathogenesis of inflammatory bowel disease (IBD) but their role as non-invasive biomarkers for IBD has not been unexplored…
BACKGROUND The gut microbiome play an important role in Crohn’s disease (CD) pathogenesis. However, the extent to which interpersonal relations shape individual genetic makeup of the microbiome and its transmission in CD patients and their household members remains unknown…
INTRODUCTION: Gut dysbiosis has been associated with suboptimal antibody response after vaccination. We aimed to evaluate the oral microbiome immunity formula (SIM01) in enhancing immunogenicity after SARS-CoV-2 vaccination in vulnerable populations…