Jason Mills

This session will feature speakers who will examine at a sub-single cell level the mechanisms through which organelles shape stem cell biology and cellular plasticity. The session will focus on the role of mitochondria and autophagy in stem cells and how these regulate plasticity…

This session will feature speakers who will examine cellular plasticity in the gastrointestinal tract and its role in regeneration. The session will focus on epithelial cell responses to pathogens…

BACKGROUND: RNA-binding motif protein 47 (RBM47) is a component of the APOBEC-1 dependent C-to-U RNA editosome required for RNA editing. However, the range of targets and functions of RBM47 in intestine is unknown…

Barrett’s esophagus (BE) is a precancerous condition defined as replacement of the normal esophageal squamous epithelium with metaplastic columnar intestinal epithelium caused by chronic gastroesophageal reflux disease…

To unravel the origins of gastric cancer, we are investigating the initiation and progression of precursor metaplasias…

In the pancreas, repeated acute pancreatitis and chronic pancreatitis cause an increased risk of progression to pancreatic intraepithelial neoplasia (PanIN) and pancreatic ductal adenocarcinoma (PDAC) via a metaplastic event in the secretory acinar cell known as acinar-to-ductal metaplasia (ADM)…