Society: AGA

This session will focus on the latest advances and future outlook of engineered probiotics, highlighting how they differ from existing probiotics. Attendees will learn about the newest approaches to improving probiotics and review pre-clinical data using engineered probiotics. Presentations will cover topics such as engineered E. coli Nissle for IBD, the role of engineered probiotics in IBD, the "BioPersist" treatment for colitis, and the effects of inflammation, dosing frequency, and diet on live bacterial therapeutic engraftment in the gut. Additionally, the session will explore how Akkermansia muciniphila can relieve diarrhea-predominant irritable bowel syndrome via the inosine-A2AR-PPARγ-AQP1 axis.

Ivan Vujkovic-Cvijin

Cedars-Sinai Medical Center Inflammatory Bowel Disease Center

Appearances