Hiroshi Nittono

BACKGROUND: Hepatocellular (_25R_)26-Hydroxycholesterol (26HC) and 3β-Hydroxy-5-cholestenoic acid (3βHCA) accumulations due to chronic oxysterol 7α-hydroxylase (CYP7B1) suppression represent a major driving force for the transition from metabolic dysfunction-associated steatotic liver (MASL) to ste…