Hemanth Karnati

It is well known of the requirement of HLA-DQ2/8 for developing CeD, but only 3% of DQ2/8 carriers have CeD. Therefore, a systemic approach is required to improve the clinical utility of genetic testing and providing a better genetic risk stratification…

Background: Lynch Syndrome (LS) is a common inherited cancer syndrome which is estimated to affect 1 in 279 individuals. In the US, about 1 million individuals have LS, many of whom remain undiagnosed…