Gwo-Tzer Ho
Appearances
- DateMay 8, 2023Aconitate decarboxylase 1 (ACOD1; also known as IRG-1) is the ubiquitous source of the metabolite itaconate, which dampens inflammasome activation by preventing HIF1α production of IL-1β and prevents TNF production through NRF2 activation…
- DateMay 19, 2024BACKGROUND: Several lines of evidence show mitochondrial damage and bioenergetic failure in ulcerative colitis (UC). However, little is known about the specific pathogenic metabolic processes that influence epithelial function and repair in UC1…