Gareth-Rhys Jones

Appearances

ACONITATE DECARBOXYLASE 1 (ACOD1) REPRESENTS A CRUCIAL REGULATOR OF MONOCYTE RECRUITMENT, SURVIVAL AND PROINFLAMMATORY STATUS IN INTESTINAL INFLAMMATION
Date
May 8, 2023
Aconitate decarboxylase 1 (ACOD1; also known as IRG-1) is the ubiquitous source of the metabolite itaconate, which dampens inflammasome activation by preventing HIF1α production of IL-1β and prevents TNF production through NRF2 activation…
Presenter
Gareth-Rhys Jones
Speakers
Lizi Hegarty
Wouter T'Jonck
Claire Adams
Broc Drury
Adam Byrne
Gwo-Tzer Ho
Calum Bain
MULTIPLE INFLIXIMAB BIOSIMILAR SWITCHES APPEAR TO BE SAFE AND EFFECTIVE IN A REAL-WORLD INFLAMMATORY BOWEL DISEASE COHORT
Date
May 7, 2023
Switching from originator to biosimilar infliximab (IFX) is effective and safe. However, data on multiple switching are scarce. The Edinburgh IBD unit has undertaken three switch programmes: (1) Remicade to CT-P13 (2016), (2) CT-P13 to SB2 (2020), and (3) SB2 to CT-P13 (2021)…
Presenter
Beatriz Gros
Speakers
Nikolas Plevris
Nathan Constantine-Cooke
Mathew Lyons
Claire O'Hare
Colin Noble
Ian Arnott
Gareth-Rhys Jones
Charlie Lees
Lauranne Derikx