Florian Rieder

SOCIETY: AGA

BACKGROUND AND AIMS: A treat-to-target (TTT) strategy of striving for symptomatic and endoscopic remission is recommended for the management of inflammatory bowel diseases (IBD). Yet, real-world uptake of TTT strategies has been modest…

Background: Mesenteric fat wrapping around the intestinal wall, so called ‘creeping fat’ (CF), is spatially linked with stricture formation in Crohn’s disease (CD)…

BACKGROUND: Inflammatory bowel disease (IBD)-associated intestinal fibrosis is a significant clinical problem. Excessive accumulation of extracellular matrix (ECM) derived from intestinal myofibroblasts (HIMF) is a hallmark of intestinal strictures…

Intestinal fibrosis is a significant clinical challenge in inflammatory bowel diseases, but no effective anti-fibrotic therapy is currently available. GCGR and GLP1R are both peptide hormone receptors involved in energy metabolism of epithelial cells…

Eosinophilic esophagitis (EoE) is a chronic immune mediated esophageal condition leading to dysphagia, strictures, and food impactions. Endoscopic biopsies remain the gold standard for diagnosis…

_INTRODUCTION:_ Despite effective anti-inflammatory therapies, ~70% of CD patients require surgery in their lifetime, due to fibrostenotic strictures linked to excess extracellular matrix (ECM) deposition…

The evaluation of volatile organic compounds (VOCs) in exhaled breath shows promise as an entirely non-invasive strategy to evaluate for inflammation with high patient acceptance…

SOCIETY: AGA

This session highlights the best of the best in basic and clinical science inflammatory bowel diseases research submitted to DDW 2025 and will cover novel genetic variants and gene expression patterns linked with disease, recent findings on the role of the gut microbiota on disease pathogenesis and…