INTRODUCTION: We aimed to investigate the relationship between consumption of ultra-processed foods (UPFs) and: 1) active symptomatic disease and 2) intestinal inflammation in a cohort of adults living with inflammatory bowel disease (IBD)…
Genetic and environmental influences contribute to Crohn’s disease (CD) development. However, the relationship between these two factors is unclear, limiting insights into CD pathophysiology, as well as interventions to prevent disease…
Background: _LRRK2_ variants (G2019S/N2081D) that increase Parkinson’s disease (PD) and Crohn’s Disease (CD) susceptibility are associated with LRRK2 kinase hyperactivity and suppress autophagy, suggesting that LRRK2 kinase inhibition, a strategy being explored for PD treatment, may also benefit CD…