Elizabeth Newberry

BACKGROUND: Alcohol-associated hepatitis (AH) is the active inflammatory state of alcohol-associated liver disease (ALD). AH varies in severity from mild to severe with mortality rates reaching 30-50% in severe AH…

Background: Genetic variants (MTTP, TM6SF2, FABP1) that modulate hepatic steatosis are linked to increased hepatocellular carcinoma (HCC). Liver specific deletion of Mttp (Mttp-LKO) or Tms6sf2 increase fibrosis, steatosis and HCC, while Dgat2-LKO mice show decreased steatosis but not fibrosis…

BACKGROUND: Therapeutic approaches to impair intestinal lipid absorption are widely employed in the management of obesity and metabolic dysfunction…