Elizabeth Angerman

A key feature in intestinal immunity is the dynamic intestinal barrier, which separates the host from resident and pathogenic microbiota through a mucus gel impregnated with antimicrobial peptides…

INTRODUCTION: Missense mutations in the epithelial NADPH oxidase DUOX2 are associated with strictures in children with Crohn’s Disease (CD)…

To date, genome-wide association studies (GWAS) have identified 418 independent genetic risk loci contributing to inflammatory bowel disease (IBD) and its two subtypes: ulcerative colitis (UC) and Crohn’s disease (CD) (PMID:37156999)…