Edoardo Savarino

Discerning whether laryngeal symptoms are related to reflux (laryngopharyngeal reflux; LPR) is a challenge. Consequently, patients see numerous specialists, undergo multiple diagnostic tests and empirically trial proton pump inhibitors (PPIs), often with inconsistent response…

BACKGROUND: Prevention of postoperative recurrence (POR) in Crohn’s disease (CD) after ileo-colonic (IC) resection is still a highly debated topic. Prophylactic immunosuppression after surgery is currently recommended in presence of at least one clinical risk factor (RF)…

Dysphagia and chest pain are the common symptoms in achalasia. The mechanisms underlying such symptoms are not completely understood. The two symptoms can be triggered by mechanical stimulation via the sensory vagal and spinal afferent nerve fibers…

According to the Lyon 2.0 consensus, patients with laryngopharyngeal reflux (LPR) symptoms should undergo upfront pathophysiologic tests to evaluate for conclusive evidence of reflux prior to medical management…

BACKGROUND: Pathophysiology of GERD is complex and esophageal motility disorders are frequently contributing to the disease…

There is no consensus on the definition of failure after treatment in patients with esophageal achalasia. Indeed, the Eckardt score (ES) is commonly used to define clinical outcome, but objective metrics based on high-resolution manometry (HRM) or other diagnostic methods are lacking…