BACKGROUND: Colonic polyposis, which is a risk factor for colorectal cancer (CRC), can be driven by a pathogenic variant in a polyposis gene. However, in many cases germline genetic testing is negative, leaving the cause of the polyposis unknown…
Pancreatic cancer (PC) screening is recommended in high-risk individuals (HRIs) with familial and genetic risk factors. Endoscopic ultrasound (EUS) and magnetic resonance imaging (MRI) are used in combination as preferred screening modalities…
Endoscopic surveillance of Barrett’s esophagus (BE) is recommended to identify dysplasia (low grade [LGD], high grade [HGD]) or adenocarcinoma [EAC]) for endoscopic intervention. However, this paradigm is limited by sampling error and subtle endoscopic changes, leading to missed HGD and EAC…