Douglas Corley

Handout [https://ddw.digitellinc…

Early-onset colorectal cancer (EOCRC, i.e., CRC diagnosed <50 years) has increased dramatically over the past three decades. However, little is known about what may be driving this alarming trend…

BACKGROUND: The fecal immunochemical test (FIT) is widely used for colorectal cancer (CRC) screening, but there are no published randomized trials or well-designed observational studies on its effectiveness and whether effectiveness varies by cancer location or demographic groups…

In 2019, a BMJ Rapid Recommendation panel judged that for adults with a predicted 15-year risk of CRC below 3%, the benefits of colorectal cancer (CRC) screening would not outweigh the burdens and potential harms. The panel recommended against CRC screening for these individuals…

Prior studies showed that the benefits, harms, and costs of colorectal cancer (CRC) screening at older ages highly depend on a patient's sex, health, and screening history. However, these studies were not directly informed by stratified data on CRC risk…