INTRODUCTION: Due to its rarity, anal adenocarcinoma (AA) does not have a standardized staging system. The tumor (T) stage of an adenocarcinoma arising from the anal canal could be based on depth of invasion, as for rectal adenocarcinoma, or on size, as in anal squamous cell carcinoma…
BACKGROUND: In the treatment of locally advanced rectal cancer (LARC), there has been a paradigm shift towards the routine use of total neoadjuvant treatment (TNT). Despite its growing acceptance, there are limited studies examining factors predictive of response to TNT…