Diane Bimczok

BACKGROUND: Perianal fistulae are highly morbid complications of Crohn’s disease (CD) with a cumulative incidence of 20-25%; despite demonstrated efficacy of infliximab treatment, estimates of complete resolution are only 20-30%. Ultimately, 20% of patients will require proctectomy…

Each day the stomach is exposed to outside antigens, and the immune system must discriminate between innocuous environmental substances and harmful pathogens such as _Helicobacter pylori. _This is achieved through antigen sampling by antigen presenting cells (APCs) such as dendritic cells (DCs)…