Cunzheng Zhang

Preconception health affects not only fertility but also offspring health. Maternal gut dysbiosis may be related to intestinal development in offspring, but there is no evidence of the relationship between the preconception gut microbiota and offspring enteric nervous system (ENS) development…

Anxiety is one of the common diseases of postmenopausal women. Our previous study showed that berberine, a natural alkaloid, could alleviate ovariectomized (OVX)-induced anxiety-like behaviors and enrich _Akkermansia muciniphila_ (AKK) in rats…

Brain-gut-microbiota axis (BGMA) disorder is an important pathophysiology of irritable bowel syndrome (IBS). There are still unclear how brain affects gut microbiota. Colon belongs to hypoxic environment, thus forming gut microbiota with obligate anaerobic bacteria as dominant strain…

Dietary supplements are widely used in functional foods for its health benefits. However, the efficacy of the combination of red yeast rice, phytosterol ester and lycopene (RPL) in the regulation of glucose and lipid metabolism disorders and obesity hasn’t yet been studied…

Gut microbiota affect the development of visceral hypersensitivity and gut dysmotility in irritable bowel syndrome (IBS). Recent studies found the mechanoreceptor Piezo2 affects gastrointestinal functions and may also affects visceral sensitivity…