Colette Deslandres
Appearances
- DateMay 8, 2023Aconitate decarboxylase 1 (ACOD1; also known as IRG-1) is the ubiquitous source of the metabolite itaconate, which dampens inflammasome activation by preventing HIF1α production of IL-1β and prevents TNF production through NRF2 activation…
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Speakers
McMaster UniversitySinai Health SystemUniversity of Manitoba - DateMay 8, 2023BACKGROUND The gut microbiome is central to Crohn’s disease (CD) pathogenesis but the relative contribution of different environmental factors to disease compositional variation is unknown…
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McMaster UniversityUniversity of ManitobaSinai Health System - DateMay 8, 2023BACKGROUND: Perianal fistulizing complications (PFC) of Crohn’s disease (CD) are highly morbid and difficult to treat. Despite the advent of biologic medications, antibiotics remain a mainstay of PFC treatment…
Speakers
Centre Hospitalier Universitaire Sainte-JustinePresenter