Christine Catinis

Background: Immune checkpoint inhibitors (ICIs) are used to treat several malignancies but predispose to systemic autoimmune inflammation referred to as immune-related adverse events (irAE). Upper and lower gastrointestinal (GI) tract inflammation are commonly encountered toxicities…

INTRODUCTION: Radiofrequency ablation (RFA) is an emerging therapeutic consideration for pancreatic ductal adenocarcinoma (PDAC), as studies show it induces coagulative necrosis and a host adaptive immune response…

In patients with sucrase-isomaltase deficiency (SID), sucrose is poorly metabolized by a specific disaccharidase in the intestinal brush border. Sucrose maldigestion promotes bacterial fermentation which can lead to symptoms of diarrhea, bloating, and abdominal pain…