Carole Macaron

Polypectomy decreases colorectal cancer (CRC) incidence and mortality. 19% of post-colonoscopy colorectal cancers (PCCRC) are found due to incomplete polypectomy…

_BACKGROUND AND AIMS: _Preclinical data shows mTOR pathway upregulation in Familial Adenomatous Polyposis (FAP). Inhibition of this pathway by rapalogues, like rapamycin, suggests promising results, but poor drug bioavailability and toxicity limited effective use of these drugs in FAP trials…