Arianna Brevi

BACKGROUND: Ulcerative colitis (UC) is a prevalent inflammatory disease of the colon, and it associated with lower levels of secondary bile acids and bile salt hydrolase (BSH) activity. Our lab has demonstrated that native bacteria can serve as chassis to functionally manipulate the gut microbiome…

BACKGROUND: Alterations in the gut microbiome have significant implications for metabolism and can modulate gene expression in different host tissues, thereby contributing to the occurrence of insulin resistance and type 2 diabetes…

BACKGROUND: To properly assess the robustness and translatability of a bacterial live biotherapeutic product (LBP) to survive and perform in the gastrointestinal tract, a complex microbiota is required…