Andrew Chan
Massachusetts General Hospital
Appearances
- DateMay 8, 2023This annual session will provide DDW attendees the opportunity to hear opposing viewpoints from leading GI experts on the most challenging issues in clinical gastroenterology and hepatology, in a debate format…
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University of Virginia Health SystemMassachusetts General Hospital - DateMay 8, 2023BACKGROUND: Marine omega-3 fatty acids (MO3FAs) - which include eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA) - are fatty acids that have anti-inflammatory properties, reducing C-reactive protein (CRP) and proinflammatory cytokines…
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Massachusetts General Hospital - DateMay 8, 2023SOCIETY: AGA
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Massachusetts General HospitalIndiana University School of Medicine - DateMay 8, 2023BACKGROUND: Aspirin has been known for its chemopreventive effect against various cancers. Evidence for the chemopreventive effect of the very long-term use of aspirin is still uncertain…
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Washington University School of Medicine/Barnes-Jewish HospitalSpeakers
Massachusetts General HospitalMassachusetts General HospitalWashington University - DateMay 8, 2023BACKGROUND The gut microbiome is central to Crohn’s disease (CD) pathogenesis but the relative contribution of different environmental factors to disease compositional variation is unknown…
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Massachusetts General HospitalMassachusetts General HospitalMassachusetts General HospitalMassachusetts General Hospital EMPIRIC DIETARY INFLAMMATORY PATTERN (EDIP) IS INVERSELY ASSOCIATED WITH RISK OF MICROSCOPIC COLITIS
DateMay 8, 2023BACKGROUND The gut microbiome is central to Crohn’s disease (CD) pathogenesis but the relative contribution of different environmental factors to disease compositional variation is unknown…Presenter
Massachusetts General HospitalSpeakers
Massachusetts General HospitalMassachusetts General HospitalMassachusetts General Hospital- DateMay 6, 2023The microbiome plays a central role in intestinal inflammation in IBD. It is influenced by environmental factors included diet…
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Massachusetts General HospitalMassachusetts General HospitalMassachusetts General Hospital - DateMay 6, 2023The microbiome plays a central role in intestinal inflammation in IBD. It is influenced by environmental factors included diet…
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Washington UniversityMassachusetts General HospitalMassachusetts General HospitalMassachusetts General HospitalMassachusetts General Hospital - DateMay 9, 2023BACKGROUND AND AIMS: Chemoresistance is a major cause of colorectal cancer (CRC) recurrence and death. The critical role of gut microbiome in the efficacy of CRC chemotherapy remains unclear…
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 6, 2023BACKGROUND: Diet is known to alter the risk of depression. Increasing data also demonstrate a causal role of the gut microbiome in mental illness, via the gut-brain axis. However, it remains unclear how diet and the microbiome mechanistically influence depression risk in humans…
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 9, 2023We and others have demonstrated a tight coupling between dietary intake, gut microbial ecology, and near-term alterations in cardiometabolic biomarkers in the ZOE PREDICT-1 study (Zeevi 2015; Asnicar & Berry 2021)…
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 9, 2023We and others have demonstrated a tight coupling between dietary intake, gut microbial ecology, and near-term alterations in cardiometabolic biomarkers in the ZOE PREDICT-1 study (Zeevi 2015; Asnicar & Berry 2021)…
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- DateMay 8, 2023BACKGROUND: Through shotgun metagenomic sequencing, we identified the depletion of probiotic species_ Lactobacillus acidophilus_ in stools of mice with non-alcoholic fatty liver disease-associated hepatocellular carcinoma (NAFLD-HCC)…
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Massachusetts General HospitalHarborview Medical CenterMassachusetts General Hospital - DateMay 9, 2023Colorectal cancer (CRC) remains a leading cause of cancer related mortality worldwide…
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 19, 2024
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 19, 2024BACKGROUND Growing evidence links high ultra-processed food (UPF) intake to various diseases, including colorectal cancer (CRC). However, the metabolomic changes underlying this relationship remain unknown…
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- DateMay 20, 2024BACKGROUND: Proton pump inhibitor (PPI) use has been linked to alterations in gut microbial communities, but prior studies have been limited to describing broad differences in microbial abundance…
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 20, 2024BACKGROUND: Primary bile acids (PBA) and their gut microbial metabolites (secondary BA [SBA]) modulate immune function and can contribute to intestinal inflammation and tumorigenesis. Diet alters the production and metabolism of BAs…
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 20, 2024BACKGROUND: The long-term risk of colorectal cancer (CRC) incidence and mortality after negative colonoscopy screening (NCS) according to individuals’ risk profiles remains unknown…
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Massachusetts General HospitalPresenter
- DateMay 18, 2024Metabolic dysfunction-associated steatotic liver disease (MASLD) is highly prevalent and a leading cause of liver-related morbidity and mortality…
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 19, 2024BACKGROUND: We derived a polygenic risk score (PRS) for diverticulitis based on known susceptibility loci for diverticular disease and investigated its joint association with body mass index (BMI), a risk factor for diverticulitis…
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- DateMay 19, 2024Gallstone disease is highly prevalent and costly in the USA: over 40 million people are affected with estimated annual health costs of $4 billion…
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- DateMay 19, 2024BACKGROUND: The detrimental impact of diverticulitis on quality of life and health care expenditures, particularly among those with recurrent episodes is substantial…
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- DateMay 19, 2024BACKGROUND: Coupled with well-characterized host genetic susceptibilities and environmental risk factors, alterations of gut microbial communities contribute to risk and severity of the inflammatory bowel diseases (IBD) and their subtypes, Crohn’s disease (CD) and ulcerative colitis (UC)…
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 18, 2024BACKGROUND: Epidemiologic studies have identified numerous dietary and lifestyle risk factors for Crohn’s disease (CD). However, the causal relationship between these factors and CD is unknown. Randomized trials of lifestyle interventions are unlikely to be performed due to limited feasibility…
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Massachusetts General HospitalMassachusetts General HospitalMassachusetts General HospitalMassachusetts General Hospital - DateMay 18, 2024BACKGROUND: Increased dairy consumption has been linked to the development of chronic inflammatory disorders and autoimmune diseases. Little research has been done to explore the relationship between dairy consumption and risk of inflammatory bowel disease (IBD)…
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Massachusetts General HospitalMassachusetts General HospitalMassachusetts General HospitalMassachusetts General Hospital - DateMay 21, 2024BACKGROUND: Diet and the gut microbiome are both established modulators of inflammation. However, their combined effect in shaping systemic inflammation remains unknown…
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Massachusetts General Hospital - DateMay 18, 2024INTRODUCTION: Emerging evidence has linked the gut microbiome to cognitive aging. Antibiotic use can rapidly reduce bacterial diversity and lead to dysbiosis that persists for months to years, potentially impairing cognitive function…
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Massachusetts General Hospital - DateMay 18, 2024INTRODUCTION: Controversies about the long-term health consequences of low-carbohydrate diets (LCD) persist…
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Massachusetts General HospitalMassachusetts General Hospital - DateMay 18, 2024INTRODUCTION: The incidence of early-onset colorectal cancer (EOCRC) has been increasing worldwide over the last decade…
- DateMay 21, 2024BACKGROUND: The gut microbiome is increasingly recognized as an important factor modulating intestinal inflammation, tumorigenesis, and immunological functions…
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Massachusetts General Hospital - DateMay 21, 2024BACKGROUND: Several observational and randomized studies have found an association between aspirin use and lower risk of colorectal cancer (CRC) incidence and mortality…
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Massachusetts General Hospital - DateMay 21, 2024
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Massachusetts General Hospital - DateMay 21, 2024
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