Amanda Blankenberger

BACKGROUND: In irritable bowel syndrome (IBS), insufficient suppression of proteolytic activity (PA) leads to intestinal barrier disruption and visceral hypersensitivity. Our work shows host PA is suppressed by microbial β-glucuronidase (GUS) activity…

BACKGROUND: Approximately 15% of individuals develop post-infection irritable bowel syndrome (PI-IBS) after _Campylobacter_ infection. Our previous work shows 40% of PI-IBS patients have high fecal proteolytic activity (PA) and changes in microbiota composition…

SOCIETY: AGA This session will delve into the cutting edge research on the bidirectional communication between the gut and the brain, and delineating the role of microbial communities in dysregulation of the gut brain axis…