Adrian Krainer

BACKGROUND: Diets high in animal fat and low in plant fiber increase colorectal cancer (CRC) risk, while diets high in fiber, but low in animal fat, are protective. Bacteria present in the colon produce beneficial and harmful metabolites from our diets…

BACKGROUND: Obesity and pro-inflammatory alterations of the gut microbiome are risk factors for gastrointestinal (GI) cancers, including liver cancer (HCC). Dysregulated TGF-β signaling through Smad3 and βII-Spectrin and loss of CEACAM1 activity are implicated in fatty liver disease…